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KMID : 0903520070500030178
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2007 Volume.50 No. 3 p.178 ~ p.186
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Synthesis and Phytopathogenic Activities of Isopropylphenyl Derivatives
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Choi Won-Sik
Jang Do-Yeon
Choi Kyoung-Gil
Lee Byung-Ho
Kim Tae-Jun
Jung Bong-Jin
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Abstract
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42 compounds such as ester, sulfonyl ester, phosphoyl ester and ether derivatives of 4-isopropylphenol (I) and 2-isopropylphenol (II) were synthesized. These derivatives were identified by IR, GC/MS and 1H-NMR spectra. Their in vitro antifungal activities were tested against 10 plant pathogenic fungi. Among them, several compounds showed potent in vitro antifungal activity. The selected compounds showing potent in vitro antifungal activity were tested for their in vivo antifungal acitvities against 5 plant diseases such as rice blast, rice sheath blast, cucumber anthracnose, cucumber gray mold and tomato late blight. As a result, 2-isopropylphenyl piperonyloate (II-7a) showed a potent in vivo antifungal activity against cucumber anthracnose and tomato late blight, 4-isopropylphenyl 4-methoxybenzenesulfonate (I-6b) effectively inhibited the development of rice blast.
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KEYWORD
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Antifungal activity, 2-Isopropylphenol, 4-Isopropylphenol, Phytopathogen
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